Jay Mohr says estranged wife Nikki Cox has a 'drug problem which makes her an unfit parent'... claims son was over-medicated and vomited in sleep

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Comedian Jay Mohr has painted a tragic picture of his actress wife's life in new court documents.

The Gary Unmarried star, filed for divorce from Nikki Cox for the second time in December and has now applied to for sole custody.

According to court documents obtained by TMZ, he is alleging the Las Vegas star has a drug problem and it is putting their son at risk.

Serious claims: The Gary Unmarried star, filed for divorce from Nikki Cox (pictured 2009) for the second time in December and has now applied to for sole custody alleging she has a drug problem and it is causing their five-year-old son to regress and putting his safety at risk 

The 46-year-old Ghost Whisper star said in the court documents that Nikki's drug issues are causing their five-year-old son to regress but did not specify how.

He did, however, claim that the actress has put son Meredith's safety at risk a number of times.

TMZ reports that Nikki allegedly gave the boy 'a double dose of flu medicine that caused the boy to vomit in his sleep'.

Court documents: TMZ reports that in the documents it says Nikki (pictured 2009) gave the boy 'a double dose of flu medicine that caused him to vomit in his sleep'

The star also alleges, TMZ reports, that his estrange wife 'doesn't set boundaries' and their child is allowed to watch television and eat candy till 2am.

This is not the first time the comedian has accused his ex of having drug issues.

The first time he filed for divorce in July he wanted full custody of their child, as he claimed the Las Vegas actress suffers from depression and that her self-medication has led to a 'serious' drug problem that puts their boy at risk. 

In his latest filing Jay said, according to TMZ, that his wife has tried to take her life twice.

The 38-year-old also told her estranged husband that she was pregnant in January, the website reports, but Jay dismissed the claim as he is azoospermic - which means his semen contains no sperm rendering him infertile.

This is the latest development in the rocky relationship which saw Jay file for divorce in July then withdraw the request declaring was 'madly in love' with the Las Vegas star, before re-filing in December. 

The Gary Unmarried star has cited irreconcilable differences as the reason he wants to end their 10-year union.

At the time he, according to TMZ, he wanted joint legal and physical custody of their son.

Baby news? The 38-year-old also told her estranged husband that she was pregnant in January, the website reports, but Jay (seen here 2006) dismissed the claim as he is azoospermic - which means his semen contains no sperm rendering him infertile

In addition, the Ghost Whisperer favourite stated in his legal papers they have a prenuptial agreement that explains how their money and assets should be divided.

Jay also shares a fourteen-year-old son Jackson with his ex-wife Nicole Chamberlain. They split in 2004. 

They tied the knot in 2009 after meeting when Jay was a guest star on Las Vegas.

Not any more: He previously gushed over his wife on Twitter, saying they are 'madly in love' after filing for divorce for the first time a week prior